Transcription Factor Browser

Detailed Locus Information for CNAG_03409T0
Species Cryptococcus neoformans var. grubii H99
Gene Annotation osomolarity two-component system, response regulator SKN7
Gene Name SKN7
TF Family Name Winged helix repressor DNA-binding (Classification based on Fungal Transcription Factor DB)
KEGG Linkout  KEGG::CNG01750    
Genome Browser JBrowse link goes here. Sequence information also available from JBrowse.
Functional Annotation
KEGG Annotation
KO AccessionE-valueScore
K15859 2.1e-162541.7
Pfam Annotation
Pfam AccessionE-valueScore
PF00072 6.8e-2378.6
PF00447 8.7e-30100.4
Expression Data

Notation Condition Normalized Raw Expression
AYPD 30°C, concentration: 2x 10^8 cells/ml 4,455
BYPD 30°C, concentration: 5x10^7 cells/ml 5,377
CYPD 30°C, fluconazole treatment, concentration: 5x10^7 cells/ml 5,949
DYPD 30°C, SDS 0.01% treatment, concentration: 5x10^7 cells/ml 4,778
EYPD 37°C, concentration: 5x10^7 cells/ml 4,816
FYP+galactose 30°C, concentration: 2x10^8 cells/ml 5,454
Gene Disruption Strategy
Primer NamePrimer DescriptionSequence
L15' flanking region primer 1CCTCACCGATTCATTCACTG
L25' flanking region primer 2CTGGCCGTCGTTTTACTTTTCTCCCTTCTTCGCCCGAC
PO1Southern blot probe primer 1ACTTCCAATGCTCAACCCCG
PO2Southern blot probe primer 2GCAGGACAAGAAGGAGAGTG
R13' flanking region primer 1GTCATAGCTGTTTCCTGAGGTTCAAGCCCAGACTCAG
R23' flanking region primer 2AGTATCTACGGTGCTGGTGC
SO1diagnostic screening primer, pairing with B79TGAGGATGATGACTGGGGAC
Phenotype Assays
Growth
Mating Data
Virulence Factor Production
Capsule Urease
Melanin
Stress Response and Adaptation
Osmotic Stress
Oxidative Stress Heavy Metal Stress
Cell Wall Stress
Antifungal Drug Susceptibility
Virulence Data by the Insect Host Model (Galleria mellonella)
Lung Infectivity Data by the Signature-tag Mutagenesis-based Murine Host Model