Transcription Factor Browser

Detailed Locus Information for CNAG_03212T0
Species Cryptococcus neoformans var. grubii H99
Gene Annotation forkhead domain-containing protein
Gene Name HCM101
TF Family Name Winged helix repressor DNA-binding (Classification based on Fungal Transcription Factor DB)
KEGG Linkout  KEGG::CNG03610    
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Functional Annotation
KEGG Annotation
KO AccessionE-valueScore
K09413 3.3e-81145.3
K09413 3.3e-81124.2
Pfam Annotation
Pfam AccessionE-valueScore
PF00250 2.4e-5082.8
PF00250 2.4e-5082.4
Expression Data

Notation Condition Normalized Raw Expression
AYPD 30°C, concentration: 2x 10^8 cells/ml 420
BYPD 30°C, concentration: 5x10^7 cells/ml 1,057
CYPD 30°C, fluconazole treatment, concentration: 5x10^7 cells/ml 1,070
DYPD 30°C, SDS 0.01% treatment, concentration: 5x10^7 cells/ml 971
EYPD 37°C, concentration: 5x10^7 cells/ml 1,352
FYP+galactose 30°C, concentration: 2x10^8 cells/ml 794
Gene Disruption Strategy
Primer NamePrimer DescriptionSequence
L15' flanking region primer 1GACACCCAAACAAGCAAAC
L25' flanking region primer 2GCTCACTGGCCGTCGTTTTACCTGGGGTGTTTGTTTTCG
POSouthern blot probe primerTGAGGAATGCCAATGGTG
R13' flanking region primer 1CATGGTCATAGCTGTTTCCTGGGGTTCAGATTTTGGATACC
R23' flanking region primer 2GGCGAGGTGTTGTAAATCC
SOdiagnostic screening primer, pairing with B79GCGTATCTGGCATCTTGTTATC
Phenotype Assays
Growth
Mating Data
Virulence Factor Production
Capsule Urease
Melanin
Stress Response and Adaptation
Osmotic Stress
Oxidative Stress Heavy Metal Stress
Cell Wall Stress
Antifungal Drug Susceptibility
Virulence Data by the Insect Host Model (Galleria mellonella)
Lung Infectivity Data by the Signature-tag Mutagenesis-based Murine Host Model